Our lab explores the following topics with a focus on the mucosal interface:
1. Interactions of the commensal microbiota with viruses (such as murine norovirus or MNoV) and bacterial pathogens, and the regulation of these interactions by the intestinal innate immune system.
2. Viral evolution and phenotypic alterations in different immunological and anatomical contexts, using murine norovirus (MNoV) as a model.
3. Exploration of the effects of commensal bacteria on the innate immune system, with a focus on type III interferons, also known as IFN-lambda, and the effects of antibiotics (Abx) treatment.